Join the Global Health Justice Partnership and the Gruber Program of Global Justice and Women’s Rights for this virtual symposium on addressing barriers to gender affirming care in selected African countries. The symposium explores recent gains in the visibility of transgender and gender diverse identities in the African region, largely on account of trans activism and including recent court judgements affirming trans identities, alongside the multiple barriers and intersectional discrimination in access to gender-affirming care. Gender affirming care in the African region requires not just a debate about the responsiveness of stakeholders to the principles of equality and non-discrimination, human dignity, participation and accountability, but also a broader debate about its epistemology to render bio-medical interventions originating in industrialised countries relevant to African social, political and legal systems. This is strategically necessary for mobilising not just financial but also political and cultural resources for institutionalising gender affirming care. The symposium is structured as a dialogue, with Botswana, Eswatini, Kenya, South Africa, Uganda and Zimbabwe serving as pivots for discussion.